Weekly Spotlight - 31.10.24

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In the News

Shared Decision Making in Rheumatology: Identifying Key Measurement Instruments

The OMERACT team is focused on standardizing shared decision-making in rheumatology. They have reviewed numerous studies, identifying 220 potential instruments. However, only a few meet all necessary criteria. The next steps involve aligning these tools with core domains and possibly developing new instruments.

Certolizumab Pegol Outperforms Adalimumab in Rheumatoid Arthritis Treatment

Recent findings indicate that certolizumab pegol demonstrates superior efficacy compared to adalimumab in patients with high rheumatoid factor. Unlike adalimumab, certolizumab maintains consistent drug concentrations and achieves better clinical outcomes. The absence of an Fc fragment in certolizumab appears to contribute significantly to its effectiveness.

Filgotinib Shows Long-Term Efficacy in Rheumatoid Arthritis Treatment

Filgotinib, a selective JAK1 inhibitor, has shown sustained efficacy in rheumatoid arthritis treatment over a three-year period, with no new safety concerns reported. Despite regulatory hesitations in the U.S. regarding potential sperm issues, the drug has received approval in Europe and Japan, and its efficacy is comparable to other JAK inhibitors.

Coping with Chronic Illness: A Journey of Resilience and Adaptation

The author shares a personal account of being diagnosed with rheumatoid arthritis and lupus at the age of 24, reflecting on the resilience and adaptation required in managing chronic illness. Despite ongoing pain and fatigue, the author emphasizes the importance of balancing daily responsibilities, embracing self-care, and celebrating personal achievements such as completing a doctorate.